Chris Lukezic has been one of the US's better milers for some time, but despite his 3:33, I've never considered him to be one of the next "truly great" milers. He didn't seem to have the speed (his 800m PR is just 1:47.75) nor the range (his 5000m PR is 13:52.60). But that may be changing, since he's just done his first stint at altitude and he's been putting in some heavy base work.
There's a nice interview with Chris at Runner's World. He covers a range of topics, but it's his experience in 2007-2008, and the way he views Nick Willis' performance, that offer the best lesson to other runners:
Chris shows me in this quote that he has the mindset of a successful individual. He builds confidence from the successes of those he relates to, and he does not attribute their superior performances to talent, but rather to their hard work, preparation, or other variable quality. I think we'll see more big things from Chris in the future, and given that he's only 24 years old, we could be seeing them for a long time!